Hydrofluoric acid skin exposure or poisoning hypocalcemia induced by various agentsĨ and 24 hours: 30 g or 30 vials (10%, 10 mL)Ĭalcium Gluconate gel/ Calgonate 2.5% gel® Special Access CDC 1-770-488- 7100 California call: 1-91 LA call: 1-21Ĭalcium channel blocker poisoning hypocalcemia induced by various agentsĬan cause tissue necrosis if extravasation occurs – use large vein for infusion OR use calcium gluconate injection (see below)Ĩ and 24 hours: 10 g or 10 vials (10%, 10 mL) Only available through the state health department (CA) or CDC IV bolus dosing for reversal of sodium channel blocker toxicity monitor alkalemiaĨ hours: 63 g (750 mEq) or 750 mL of 8.4% solutionĢ4 hours: 84 g (1000 mEq) or 1 L of 8.4% solutionīotulinum antitoxin / H- BAT- heptavalentĬontact local or state health department for reporting and to facilitate access to the antitoxin. Sodium channel blocker toxicity & urinary alkalinization Heavy metal poisoning (Arsenic, mercury, lead and gold)Ĩ hours: 800 mg or 3 amps (100 mg/mL, 3 mL each)Ģ4 hours: 2400 mg or 8 amps (100 mg/mL, 3 mL each) Special Access: (Merck, 1-800-672- 6372) Merck Order Management Center, 1-80, will drop ship up to 2 vials. Also stocked in the Strategic National Stockpile: for mass casualties, the SNS may provide supplies for first 48 hours (coordinated by state department of health and emergency response system).Ĩ Hours: 100 mg or 13 vials (0.4 mg/mL, 20 mL each)Ģ4 hours: 200 mg or 26 vials (0.4 mg/mL, 20 mL each)Īntivenom, Crotalidae Polyvalent Immune- FAB(ovine)/ Cro-Fab®Įither antivenom product equally efficaciousĪntivenom, Crotalidae Immune- FAB 2(equine)/ Anavip®Īntivenom, Black Widow Spider/ Antivenom (Latrodectus Mactans)®Įquine base risk of allergic hypersensitivity May require large amounts in severe cholinesterase inhibitor poisoning.
Organophosphate/ carbamate insecticide poisoning and other cholinesterase inhibitors (eg, warfare agents) bradycardia induced by a variety of toxins
Medical centers that might expect to receive large numbers of patients in a single incident should stock larger amounts of antidotes or have an effective and efficient drug sharing/transfer procedure in place to rapidly obtain additional antidotal supplies. For medical centers choosing to stock antidotes, the suggested stocking level is based on the dose needed to treat a single 100 kg patient for 8 hours and for 24 hours.
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